Urugo

 

Kolajenini igice cy'ingenzi cya matrix yo hanze y'umubiri (ECM), iboneka cyane cyane mu ruhu rw'umuntu, mu magufwa, mu kajagari, mu menyo, mu mitsi, mu mitsi no mu miyoboro y'amaraso. Ni kandi poroteyine y'ingenzi mu miterere y'ingingo zihuza umubiri.

Kolajeni ni igice cy'ingenzi cy'uruhu rw'umuntu. Hamwe n'ingano nto ya elastine, ikora urusobe rusanzwe rwa fibre za kolajeni, ibyo bigatuma uruhu rukomera kandi rukagira ubushobozi bwo gutwara ubushuhe.

Ariko, ibintu nk'ubusaza, imirasire ya UV, kunywa itabi, n'imibereho mibi bituma kolajeni igabanuka. Iyo kolajeni itakaye cyane, ibimenyetso byo gusaza nko gutakaza ubushobozi bw'uruhu, kugwa, iminkanyari, ibara ry'uruhu, kuma, uruhu rudakomeye, n'uruhu rworoshye bigaragara buhoro buhoro.

None se, niba kolajeni irimo kugabanuka, ese ibikomoka kuri kolajeni mu kanwa bishobora kugabanya igihe cyo gusaza?

Ese peptide za kolajeni zo mu kanwa zishobora kwinjizwa n'umubiri?

Ibikoresho bya kolajeni bisanzwe biri ku isoko bivuga kolajeni, ntabwo ari kolajeni.

KolajeniPeptide ni uruvange rwa peptide zifite uburemere buke bwa molekile zifite uburemere bungana na Da 2000 kugeza 10.000 zikomoka kuri kolajeni (Da 300.000). Ugereranyije na kolajeni ifite uburemere bwinshi bwa molekile, peptide za kolajeni zifite uburemere buke bwa molekile kandi zoroshye gusya no kwinjiza.

Byongeye kandi, dipeptide na tripeptides biri muri peptides za kolajeni zitwarwa kandi zigashyirwa mu buryo butaziguye nk'peptides na poroteyine itwara oligopeptide (PepT1) iba mu turemangingo tw'impiswi tw'amara mato. Zishobora kwibasirwa ahantu runaka mu mubiri kugira ngo zikore neza kandi zigire akamaro.

Watanabe-Kamiyama M. n'abandi bafashe peptide za collagen zifite label ya 14C mu ngingo zitandukanye z'imbeba, maze bitegereza uko zikwirakwirapeptide za kolajeni.

Ubushakashatsi bwagaragaje ko peptides za kolajeni mu kanwa zakwirakwijwe mu ngingo z’ingenzi mu mubiri wose nyuma yo gusya no gukurura, kandi zishyirwa by’umwihariko mu ngingo zikungahaye kuri kolajeni, cyane cyane uruhu, nyuma y’igihe runaka.

Ese peptide za Collagen zo mu kanwa zishobora kunoza imiterere y'uruhu?

Mu myaka ya vuba aha, ubushakashatsi bwinshi bwerekanye ingaruka nziza za peptides za kolajeni mu kanwa mu gutinda gusaza k'uruhu no kuvugurura uruhu.

Abashakashatsi batoranyije abakorerabushake 64 bari hagati y'imyaka 40 na 60 kugira ngo bafate 1000 mg ya peptides za collagen zifite uburemere buke mu mubiri buri munsi mu gihe cy'ibyumweru 12, maze basanga nyuma y'ibyumweru 6 umuntu anywa, amazi y'uruhu yarushijeho kwiyongera, kandi nyuma y'ibyumweru 12, iminkanyari n'ubudahangarwa bw'uruhu byarazamutse, bigaragaza ingaruka zo kurwanya gusaza. Ibisubizo byagaragaje ko uruhu rwarushijeho kugira izamuka rikomeye mu kubika ubushuhe nyuma y'ibyumweru 6 umuntu anywa ndetse n'ingaruka zo kurwanya gusaza nyuma y'ibyumweru 12.